Interaction Survival is a program to calculate either estimates of sample size or power for tests of interaction. Exponential distributions are assumed and are specified as a ratio of the hazard ratio for the treatment effect in stratum 1 to the hazard ratio for the treatment effect in stratum 2. The program allows for unequal sample size allocation in the four cells defined by the two treatment groups and two strata. An exponentially distributed competing risk is also permitted.

For further details, view the Help Document.

User Input

Program Output

Alpha

Accrual

Follow

Power

Sample Size

Comp Risk

Cell Freq Treat1/Strat1

Cell Freq Treat1/Strat2

Hazard Rate Treat1/Strat1

Hazard Rate Treat1/Strat2

Median Survival Treat1/Strat1

Median Survival Treat1/Strat2

Survival Probability Treat1/Strat1

Survival Probability Treat1/Strat2

at Time

Cell Freq Treat2/Strat1

Cell Freq Treat2/Strat2

Haz Ratio T1/T2 Strat1

Haz Ratio T1/T2 Strat2

Power

Sample Size

Hazard Rate Treat1/Strat1

Hazard Rate Treat1/Strat2

Median Survival Treat1/Strat1

Median Survival Treat1/Strat2